If you opt to hand your hotel over, you will effectively pass the responsibility of its day to day operation to the occupier. If you retain the active management, however, you will be faced with a myriad of concerns.
Homeless people are more likely in general to have respiratory problems and so be more susceptible to the virus. With the increased risk of symptoms being brought into the hotel, how do you effectively protect your staff? Supplies of PPE and regular, deep cleaning will be required.
Hotels will need systems of monitoring those who are self-isolating, with regular checks on vulnerable guests. Meals will need to be delivered to rooms, and social distancing may need to be enforced to prevent occupants from gathering in common areas. You may need to ask guests to seal their linen in bags for 72 hours before a laundry service can be provided, to prevent the spread of the virus.
Is there an increased security risk, both to personnel and property, which will require extra training for staff and security staff, especially during the quiet hours? Guests in the hotel may need more support and liaison with emergency services than during the course of regular business. Hoteliers will certainly want to ensure that fire safety systems are in working order and practice evacuation drills.